Insulin-sensitizing agents in polycystic ovary syndrome

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Effects of insulin-sensitizing agents and insulin resistance in women with polycystic ovary syndrome

OBJECTIVE The aim of this study was to investigate the effect of insulin sensitizing agents on hormonal and metabolic parameters as well as menstrual patterns in women with polycystic ovary syndrome (PCOS). METHODS One hundred and twenty-three patients with PCOS were included. Metformin was administered to patients at 1,500 mg or 1,700 mg daily for 3 months. If the patients had no improvement...

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Insulin-sensitizing agents: use in pregnancy and as therapy in polycystic ovary syndrome.

Treatment with insulin-sensitizing agents is a relatively recent therapeutic strategy in women with polycystic ovary syndrome (PCOS) and insulin resistance. The key areas addressed in this review include PCOS and the development of type 2 diabetes mellitus and gestational diabetes, as well as the use of insulin-sensitizing agents, particularly metformin, in the management of infertility in obes...

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Insulin Secretory Defects in Polycystic Ovary Syndrome

The increased prevalence of non-insulin-dependent diabetes mellitus (NIDDM) among women with polycystic ovary syndrome (PCOS) has been ascribed to the insulin resistance characteristic of PCOS. This study was undertaken to determine the role of defects in insulin secretion as well as familial factors to the predisposition to NIDDM seen in PCOS. We studied three groups of women: PCOS with a fami...

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Polycystic ovary syndrome. Polycystic ovary syndrome.

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ژورنال

عنوان ژورنال: European Journal of Endocrinology

سال: 2006

ISSN: 0804-4643,1479-683X

DOI: 10.1530/eje.1.02156